Evaluation Of Stability Research Articles

Evaluation of stability for grain yield and its attributing traits in wheat (Triticum aestivum L.)

Evaluation of stability for grain yield and its attributing traits in wheat (Triticum aestivum L.)

Selection of long-term shear strength parameters for strain softening geosynthetic interfaces (2023 IGS Rowe Lecture)

The behavior of strain-softening geosynthetic interfaces that can lead to progressive failures in lined containment facilities has been a source of confusion in slope stability evaluations for over 30 years. The paper presents fifteen mechanisms that can potentially induce displacements along strain-softening interfaces, along with measures that can be considered to reduce strain-softening displacement. New quantifications of shear strength variability that can be caused by manufacturing, installation, and construction practices are introduced. Guidance and recommendations are given that are applicable to numerical continuum as well as limit-equilibrium approaches to assist in selecting appropriate geosynthetic shear strength parameters for containment facilities that have strain-softening interfaces. While most of the paper focuses on deep-seated critical interfaces for high normal stress bottom liners, low normal stress veneer covers are also addressed.

Losartan potassium liquid formulation for paediatric hospital use: development and stability evaluation

ObjectivesThis study aimed to develop a liquid oral formulation containing losartan potassium, an angiotensin II receptor antagonist drug used for its antihypertensive activity, and to perform a preliminary stability assessment...

Synergistic boost in Fe3O4 anode performance for li-ion batteries via Zn and Cu double doping and multi-walled carbon nanotube composite integration

In this study, a novel nanocomposite material comprising pure Fe3O4 (FO), doped Zn0.5Cu0.5Fe2O4-3 (ZCFO-3), and Zn0.5Cu0.5Fe2O4-3@ Multi-walled carbon nanotube (ZCFO-3@MWCNT) nanocomposite material is carefully prepared using a simple one-step hydrothermal process. Comprehensive surface and morphological analysis are conducted using X-ray diffraction (XRD), Field emission scanning electron microscopy (FESEM), and High-resolution transmission electron microscopy (HRTEM), while compositional studies are investigated through Raman spectroscopy and X-ray photoelectron spectroscopy (XPS). The electrochemical performance is fully analyzed through Cyclic voltammetry (CV), Electrochemical impedance spectroscopy (EIS), rate capability tests, discharge/charge capacity, and cyclic stability evaluations. Among these three nanomaterials, ZCFO-3@MWCNT nanocomposite at 100 mA g−1 current density reveals the best performance, with a discharge capacity of 1974 mAh g–1, ZCFO-3 and FO reveal 1340 mAh g–1 and 1317 mAh g–1 respectively. After 800 cycles at 500 mA g−1 current density, ZCFO-3@MWCNT stays strong with a discharge capacity of 646 mAh g–1, while ZCFO-3 manages only 362 mAh g–1 and FO only 111 mAh g–1. After 1200 cycles at 500 mA g−1, the nanocomposite still delivers 518 mAh g–1. This study suggests that ZCFO-3@MWCNT could be a promising anode material for lithium-ion batteries.

Three-Dimensional Evaluation of Treatment Effects and Post-Treatment Stability of Maxillary Molar Intrusion Using Temporary Anchorage Devices in Open Bite Malocclusion

Background: We investigated treatment outcomes and post-treatment stability in 10 patients with an anterior open bite and nonsurgical orthodontics. Methods: The patients underwent maxillary molar intrusion using temporary anchorage devices (TADs) to deepen the overbite due to mandibular autorotation. Lateral cephalograms and dental cast models were obtained before treatment (T0), immediately after it (T1), and >1 year after it (T2). Skeletal and dental cephalometric changes and three-dimensional movements of the maxillary dentitions were evaluated. Results: At T0, cephalometric analysis indicated that patients had skeletal class I with tendencies for a class II jaw relationship and a skeletal open bite. During active treatment (T0 to T1), the maxillary first molar intruded by 1.6 mm, the mandibular first molar extruded by 0.3 mm, the Frankfort-mandibular plane angle decreased by 1.1°, and the overbite increased by 4.1 mm. Statistically significant changes were observed in the amount of vertical movement of the maxillary first molar, Frankfort-mandibular plane angle, and overbite. Three-dimensional (3D) dental cast analysis revealed that the maxillary first and second molars intruded, whereas the anterior teeth extruded, with the second premolar as an infection point. In addition, the maxillary molar was tipped distally by 2.9° and rotated distally by 0.91°. Statistically significant changes were observed in the amount of vertical movement of the central incisor, lateral incisor, canine and first molar, and molar angulation. From T1 to T2, no significant changes in cephalometric measurements or the 3D position of the maxillary dentition were observed. The maxillary and mandibular dentitions did not significantly change during post-treatment follow-up. Conclusions: Maxillary molar intrusion using mini-screws is an effective treatment for open bite correction, with the achieved occlusion demonstrating 3D stability at least 1 year after treatment.

IBUPROFEN INJECTABLE MICROEMULSION PREPARATION COATED BY CHITOSAN: FORMULATION, CHARACTERIZATION, IN VITRO PERFORMANCE, ANTI-INFLAMMATION ACTIVITY, AND HEMATOLOGY ASSESSMENT

Objective: This study aimed to develop, characterize, and conduct stability evaluations to ensure compliance with intravenous administration for microemulsion ibuprofen injection. In addition, hematology assessment and profile of drug release kinetics were analyzed. Methods: The formulation process commenced by introducing various chitosan concentrations into microemulsion ibuprofen injection, following a method established in a previous study. Formulation parameters studied include particle size, polydispersity index (PDI), zeta potential, kinetic of drug release, anti-inflammation activity using the 1% carrageenin induction method, and hematology assessment. Results: The results showed that the addition of 1% chitosan solution allowed for the development of the ideal microemulsion formula, with droplet size, zeta potential, and PDI of 19.37±0.32 nm,-1.53±0.12 mV, and 0.38±0.02, respectively. Kinetics of chitosan-coated ibuprofen microemulsion (MK) were governed by the squared root of time paradigm, suggesting that drug release proceeded by diffusion and was influenced by the carrier. Compared to the other groups, the paw injected with MK indicated a strong anti-inflammatory effect and did not differ significantly from the control group (p>0.05). However, Hematology analysis showed no statistically significant variations in leukocyte and erythrocyte profiles between the treatment and control groups (p>0.05). Conclusion: MK met the criteria as an intravenous preparation based on the characteristics and safety.

Studies on Quantitative Determination of Polyphenols in Seven Harvesting Times of Salvia deserta Schang Leaves and its Stability Evaluation

Introduction: Leaves of Salvia deserta Schang at seven harvesting times in the same year were collected as the materials. Method: The polyphenols were determined by the Folin–Ciocaileu method and High-Performance Liquid Chromatography (HPLC) to compare the quality of samples. The stability of polyphenols was studied under different conditions (light, temperature, pH, common additives). objective: The contents of total polyphenols in samples of different growth stages were determined by Folin-Ciocaileu colorimetry. The contents of rosmarinic acid and caffeic acid in samples of different growth stages were determined by HPLC. The stability of polyphenols in Salvia deserta Schang Leaves was investigated by measuring the change of polyphenol retention rate in different media (light, temperature, pH, oxidant, sugar, preservative, salt and citric acid) Results: The results showed that the established method is fast, simple and reliable, which is fully validated in terms of outstanding validation data. High Performance Liquid Chromatography (HPLC) for the determination of total polyphenol content can be quickly and accurately detected, reducing the error of manual determination of the content. The study of polyphenol stability was carried out using a UV spectrophotometer (UV) in order to explore the potential factors affecting polyphenol stability as much as possible and to make the study as scientific and rigorous as possible. The results of quantitative determination showed that there are obvious differences in the content of polyphenols in seven samples. The contents of total polyphenols, rosmarinic acid (RA) and caffeic acid (CA) in the samples harvested in July reached the highest level of 41.37, 26.73 and 1.05 mg/g. Conclusion: The results of the stability assay found that light could damage the stability of polyphenols in samples, especially UV light. Polyphenols are quite sensitive to high temperatures. While polyphenols are less stable when exposed to high alkali conditions and salt treatment, they are much more stable when subjected to low concentrations of redox agents, carbohydrates, and preservatives. The developed methods and stability evaluation provide valuable basis information for quality evaluation and the following use of polyphenols in S. deserta Schang leaves.

The Chemical and Optical Stability Evaluation of Injectable Restorative Materials Under Wet Challenge.

To investigate and compare the chemical and optical stability of four restorative composite materials: two injectable resins, one flowable resin and one compomer. Two injectable nano-filled composite resins: G-aeniel Universal (GU) and Beautifil Injectable XSL (BI), a flowable composite resin: Filtek Supreme Flowable (FS) and a compomer: Dyract Flow (DF), in A2 shade were tested and compared. Water sorption and solubility were conducted according to ISO4049: 2019 standard; ICP-OES and F-ion selective electrode were used to test the elemental release; Degree of conversion (DC) was obtained by using FTIR; water contact angle was obtained by static sessile drop method, and spectrophotometer was used for optical properties (ΔE*, ΔL* and TP). SPSS 28.0 was used for statistical analysis and the significant level was pre-set as α=0.05. GU performed the best in water sorption and solubility, FS had the lowest elemental release, the best colour stability, and the highest DCIM and DC24-h. DF, the compomer had the lowest, and GU and BI, the injectable composites had the largest water contact angle, respectively. Correlations were found between water sorption and water solubility. The four composite restorative materials showed different chemical and optical behaviours. Overall, composite resins performed better than compomer, while additional laboratory and in vivo tests are necessary to obtain a more comprehensive comparison between injectable and flowable composite resins. Wsp and Wsl are influenced by many common factors, and the values are highly positively related. A comprehensive understanding of materials is crucial before selecting materials for clinical practice. Composite resins rather than compomers are recommended because of their exceptional properties, which make them eligible for a wide range of clinical applications and an elongated lifespan.

Oil-based Z-isomer-rich lycopene: Efficient production in dual-media and stability evaluation

Developing a practical and efficient method for the Z-isomerization of lycopene is essential, as the Z-isomers exhibit higher biological activity and bioavailability compared to the all-E-isomer. The aim of this study was to develop an innovative approach to induce thermal Z-isomerization of (all-E)-lycopene by utilizing a dual-media system consisting of oil and ethanol in conjunction with a heat-pressure process. Specifically, the effects of reaction temperature, initial reaction pressure, ethanol volume ratio, and reaction time were investigated. The novel reaction system effectively facilitated the Z-isomerization of (all-E)-lycopene. For instance, when subjected to a reaction at 120 °C for 30 min, the total Z-isomer ratio surpassed 66%. FTIR, DSC, and XRD confirmed the presence of Z-isomer-rich lycopene dispersed in oil in an amorphous state and with a lower melting point. Moreover, an evaluation of the stability of Z-isomer-rich lycopene in olive oil revealed a decreasing trend in both lycopene concentration and total Z-isomer ratio with increasing temperature and storage time. Notably, among the lycopene isomers, (5Z)-lycopene showed the greatest stability compared to other isomers of lycopene. This eco-friendly and efficient isomerization technology is a useful approach for producing Z-isomer-rich lycopene materials.

A stability evaluation method for deep-seated toppling in the upper Lancang river, Southwestern China

Deep-seated toppling in the upper reaches of the Lancang River, southwest China involves deformations exceeding 100 m in depth. The slope deformation is initiated by river downcutting and evolves distinctive characteristics with a depth of river incision. In this study, we propose a system for evaluating the stability of deep-seated toppled slopes in different evolutionary stages. This system contains identification criteria for each evolutionary stage and provides the corresponding stability evaluation methods. Based on the mechanical and kinematic analysis of slope blocks, the specific stage of slope movement can be identified in the field through outcrop mapping, in situ tests, surface displacement monitoring, and adit and borehole explorations. The stability evaluation methods are established based on the limiting equilibrium theory and the strain compatibility between the undisturbed zone and the toppled zone. Finally, several sample slopes in different evolution stages have been investigated to verify the applicability and accuracy of the proposed stability evaluation system. The results indicate that intense tectonic activity and rapid river incision lead to a maximum principal stress ratio exceeding 10 near the slope surface, thus triggering widespread toppling deformations along the river valley. When considering the losses of joint cohesion during the further rotation process, the safety factor of the slope drops by 7%–28%. The self-stabilization of toppling deformation can be recognized by the layer symmetry configuration after the free rotation of the deflected layers. Intensely toppled rock blocks mainly suffer sliding failures beyond the layer symmetry condition. The factor of safety of the K73 rockslide decreased from 1.17 to 0.87 by considering the development of the potential sliding surface and the toe-saturated zone.

Design and fabrication of functionalized curdlan-curcumin delivery system to facilitate the therapeutic effects of curcumin on breast cancer

We developed a facile method for the fabrication of a biodegradable delivery system composed of two blocks: curdlan and curcumin. This was achieved by chemical functionalization of curdlan through tosylation, amination followed by complexation with curcumin. A comprehensive evaluation of structural characterization and component stability showed that cur-cum complex exhibited better anticancer properties with enhanced thermal properties. The cur-cum complex shows pH sensitive sustained release behaviour with higher release at acidic pH and kinetic data of drug release follows the Korsmeyer-Peppas model. The cur-cum complex has ability to block the proliferation of the MCF-7 cell line as revealed by MTT assay which showed increased toxicity of cur-cum complex against these cell lines. The results obtained from western blot analysis demonstrated that the co-administration of cur and cum effectively induced apoptosis in MCF-7 cells. This effect was observed by a considerable upregulation of the Bcl-2/Bax ratio, a decline in mRNA expression of LDHA, level of lactate and LDH activity. The results clearly depict the role of functionalized curdlan as efficient carrier for curcumin delivery with prolonged, sustained release and enhanced bioavailability, thereby improving the overall anticancer activity.

The effect of different types of leavening agents on the physical characteristics and sensory of red bean sponge cake

Red bean (Phaseolus vulgaris L.) has rapid growth in Indonesia with high production capacity. It has 50% more protein and 88% more crude fiber content than wheat flour. This makes red beans one of the potential raw materials for making sponge cake without using wheat flour. However, red bean-based products need additional food additives to improve the physical characteristics of sponge cake. The purpose of this study is to develop a sponge cake product made from red bean flour as a substitute for wheat flour with the addition of food additives (SP, TBM, ovalette, baking powder, baking soda, and cream of tartar) also to determine the effect of using the type of leavening agent on physical characteristic and preference level on red bean sponge cake. Hardness, density, swelling power, swelling stability, crumbs analysis, color properties, and sensory evaluation was conducted using six different leavening agents. Furthermore, the sample analysis was performed triplicate then analysed using one-way analysis of variance (ANOVA). Based on the physical characteristic test, the best addition of food additives is SP, TBM, and baking powder. Furthermore, red bean sponge cake with the addition of SP was the most liked by the panelists with a score of 3.79.

Stability evaluation of stored samples for routine chemistry tests

Stability evaluation of stored samples for routine chemistry tests

Pinostrobin and its derivatives as novel anti-breast cancer agents against human oestrogen receptor alpha: In silico studies of ADMET, docking, and molecular dynamics

Pinostrobin and its derivatives as novel anti-breast cancer agents against human oestrogen receptor alpha: In silico studies of ADMET, docking, and molecular dynamics

Investigation of the Effectiveness of TecnoBody Devices in Rehabilitation

With the advancement of technology, the effect of auxiliary machines used in rehabilitation is gradually increasing both in the evaluation stage and the rehabilitation stage of the treatment. The important feature of such devices is that they perform both assessment and treatment with the same device. At this stage, TecnoBody (Bergamo, Italy) devices play an active role in both assessment and rehabilitation. In this study, the effectiveness of TecnoBody devices, D-Wall, Walker View 3.0 SCX, and ProKin devices in rehabilitation was analyzed. It is reported in the literature that recently TecnoBody devices have been used significantly in evaluation, proprioceptive and stability tests have been performed with ProKin devices, and balance tests have been performed with the D-Wall device. The D-Wall device was found to be effective in therapies due to its use in rehabilitation, exergame, and biofeedback. It is observed that the Walker View 3.0 SCX device is effective in gait analysis evaluation and gait rehabilitation after surgery, while ProKin devices are effective primarily in proprioceptive, stability, and balance evaluations and then in balance and proprioceptive training. The use of TecnoBody devices in rehabilitation increases the active participation of people in therapy thanks to the visual biofeedback it applies to people, it is effective thanks to the fact that people can direct themselves during exercise and make therapy more fun with games. In addition, thanks to the personalized exercises in the D-Wall device, there are effective exercises to increase the participation of people in daily life activities, especially in neurological rehabilitation. Therefore, the use of TecnoBody devices in rehabilitation is effective.

Seepage handling using secant pile as a solution to replace curtain grouting and dam stability evaluation to optimize work on the Margatiga Dam construction project

Based on the results of a soil investigation using the bore log method carried out by the Consultant, it was found that the foundations of the spillway building and intake building are in a geological condition that is composed predominantly of sand and porous deposits or easily absorbs water, as well as rocks with the characteristics of fine tuff rock, indicating that the foundation The building is prone to seepage. The seepage treatment contained in the contract is the curtain grouting method 20 meters deep with a distance of 2 meters between points. It is necessary to carry out trial grouting in 3 location zones to be sure. Therefore, it is necessary to analyze the secant pile design. In the work on filling the dam body on the left and right sides, a review needs to be carried out to optimize the implementation of the work because it has a safety factor that is too high than the required safety factor. Secant pile design planning and cross-section evaluation calculations use software to help calculate seepage and stability analysis. Based on the results of modeling analysis calculations and evaluation of cost and implementation time calculations that meet the criteria, it is recommended to handle seepage using secant piles, namely with dimensions of 80 cm, overlap of 15 cm and a depth of up to -10 elevation and recommendations for the cross-section of the dam body, namely by modifying the slope of the section.

Laboratory Evaluation of Storage Stability for Asphalt Binder Modified with Crumb Rubber and Styrene-Isoprene-Styrene Depending on Evaluation Factors and Blending Condition.

Modified asphalt binders are still considered important in asphalt pavement. However, the comprehensive use of various modifiers is limited due to storage stability issues. Moreover, there is a scarcity of detailed analyses regarding the degree of separation for asphalt binders among each method despite the utilization of various methods to assess the storage stability of binders. Therefore, a comprehensive analysis was conducted to assess the storage stability of asphalt binder modified with a crumb rubber modifier (CRM) and styrene-isoprene-styrene (SIS), utilizing five evaluation factors following the ASTM D7173 guidelines based on four mixing methods (A: high-shear mixing method, B: low-speed agitating method, C: high-shear mixing method + low mixing method, D: low-speed agitating method + low mixing method). To produce the modified asphalt binder, the proportions of the CRM were 5% and 10% for each binder, and 10% SIS was added to all binders. The results in this study convey that (1) the addition of the modifier led to an increase in G*/sin δ with different mixing methods, but using mixing methods (C and D) for a relatively long time resulted in a lower G*/sin δ, indicating suboptimal performance; (2) through the multiple stress creep recovery (MSCR), rheological properties of Jnr and % rec exhibited trends similar to G*/sin δ evaluation, highlighting an improved elastic recovery with a higher modifier content; (3) storage stability assessment revealed consistent trends in high-shear mixing groups (A and C), while low-speed mixing groups (B and D) exhibited an elevated separation index (SI), suggesting a sensitivity to modification conditions; (4) evaluation using the MSCR method indicated that % rec with a 3.2 kPa load is effective for the sensitive assessment of binder storage stability and Jnr showed a limited sensitivity across varying loads, advocating for % rec for precise evaluation; and (5) despite permitting various tests, achieving consistent results remains challenging. Future research should explore diverse modifiers and optimal evaluation methods to enhance knowledge of binder behavior and separation dynamics.

Research on a Classification Method of Goaf Stability Based on CMS Measurement and the Cloud Matter–Element Model

The evaluation and classification of goaf stability are fuzzy and random. To address this problem, a new classification method is proposed. A cavity monitoring system is used to detect the goaf, 3DMine and FLAC3D software are used to conduct the 3D visual modeling of the scanning results, and numerical simulation analysis is performed on the goaf. According to the analysis results, the stability classification standard of the goaf is constructed, and the characteristics of each classification are described. The evaluation indicator system of goaf stability is constructed in accordance with similar engineering experience, and the evaluation indicator is weighted by using the analytic hierarchy process. The cloud–element coupling evaluation model is built, the field measured values of indicators are collected, the cloud correlation degree of goafs belonging to each stability level is calculated, the stability level is evaluated according to the principle of maximum membership degree, and the results are compared with the numerical simulation to analyze the reasons for the differences in the stability evaluation results obtained by the two methods and to improve the accuracy of the evaluation of goaf stability. The pillar stress and surrounding rock deformation are monitored in Room 1# of the inclined mining area of Shirengou Iron Mine. The monitoring results are consistent with the evaluation results, which proves the accuracy of the proposed goaf stability classification method.

Evaluation of color Stability of Different Restorative Materials Used in Pediatric Dentistry

Background: The aim of this study was to evaluate the color changes of restorative materials (Filtek z550, EverX Posterior, Dyract XP, EQUIA Forte Fill), which are frequently used in pediatric dentistry, after aging with beverages (cola, cherry juice) that children and adolescents frequently consume in their daily life. Methods: Four different restorative materials; nanohybrid composite (Filtek Z550), glass fiber reinforced bulk fill composite (EverX Posterior), polyacid modified composite resin (Dyract XP) and glass hybrid glass ionomer cement (EQUIA Forte Fill) were used. A total of 120 samples were prepared for each material using plexiglass molds with a thickness of 2 mm and a diameter of 10 mm. A total of 30 samples from each group were divided into 3 group (n=10) to be immersed in cola, cherry juice and distilled water. After the initial color measurements, the samples were stored in beverages for 7th and 14th days. Color change values (ΔE) were calculated after 7th and 14th days. Results: When the ΔE values of materials were examined, it was observed that EQUIA Forte Fill group had the highest color change and Filtek z550 group had the lowest color change. Conclusion: The glass hybrid GIC showed the most distinct color change in all time periods and beverages. ΔE values in cola and cherry juice of all resin-based restorative materials tested were less than or equal to 3.3. Therefore, color changes were clinically acceptable as they were not visually perceptible Key words: Bulk-Fill Composite Resin, Color Stability, Glass Hybrid Glass Ionomer Cement

Coke formation on different metal-modified (Co, Mo and Zr) ZSM-5 in the catalytic pyrolysis of cellulose to light aromatics

Catalytic pyrolysis of biomass is regarded as a promising method for preparing value-added products. However, the main factors limiting the development of the process at present are the low yield of value-added products and poor selectivity, especially for rapid catalyst deactivation due to coke deposition. The present study focuses on the catalytic pyrolysis of cellulose over metal Co-, Mo-, and Zr-loaded catalysts using a falling fixed bed at 600 °C to evaluate the type of coking of the catalysts as well as the effect of the different metal active sites on the formation of coke deposits. The introduction of Co and Mo metal sites increased the light aromatics yield of ZSM-5 from 128.9 mg/g to 147.2 mg/g and 143.0 mg/g. And the yield of coke deposits decreased from 8.3 to 6.8 and 5.1 wt%. The stability evaluation of the catalyst showed that the deactivation degree of ZSM-5 of the supported metal Co was lower than that of commercial ZSM-5, while the ZSM-5 of the supported metal Mo was rapidly deactivated. The deactivation of the catalysts depended more on the morphology or location of the accumulated coke than on the total amount deposited. The clogging of metal and acidic sites on the surface of the zeolite and the pore channels by the amorphous encapsulating coke was the main cause of catalyst deactivation. The metal Mo active sites promoted dehydrogenation coupling and hydrogen transfer during coke formation, forming a more highly disordered multiring structure, and the metal Co active sites were more capable of decomposing macromolecular compounds, olefins and alkanes, and promoted the formation of graphite-like structural carbon.